Cyclopamine | Inhibits hedgehog signaling

CAS:
4449-51-8
Catalog Number:
10-1082
Activity:
Inhibits hedgehog signaling
Molecular Weight:
411.63
Molecular Formula:
C27H41NO2
Solubility:
Soluble in DMSO (up to 4 mg/ml) or in Ethanol (up to 20 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

SizePriceQuantity 
5 mg$56.00
25 mg$140.00

Cyclopamine (4449-51-8) is a naturally occurring steroidal alkaloid with teratogenic activity. Blocks sonic hedgehog signaling by binding to smoothened. Antitumor activity. Cell Permeable.

References/Citations:

1) Watkins et al. (2003), Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer; Nature, 422 313

CAS:
4449-51-8
Catalog Number:
10-1082
Activity:
Inhibits hedgehog signaling
Molecular Weight:
411.63
Molecular Formula:
C27H41NO2
Solubility:
Soluble in DMSO (up to 4 mg/ml) or in Ethanol (up to 20 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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