CYM-5541 | Allosteric sphingosine-1-phosphate receptor 3 agonist

CAS:
945128-26-7
Catalog Number:
10-4493
Activity:
Allosteric sphingosine-1-phosphate receptor 3 agonist
Chemical Name:
N,N-Dicyclohexyl-5-cyclopropyl-1,2-oxazole-3-carboxamide
Alternate Name:
ML249
Molecular Weight:
316.44
Molecular Formula:
C19H28N2O2
Solubility:
Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 15 mg/ml).
Physical Properties:
Off-white solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
5 mg$45.00
25 mg$155.00

CYM-5541 (945128-26-7) is a potent and selective allosteric agonist of the sphingosine-1-phosphate receptor 3 (S1P3; EC50’s = 72.3-132 nM).1,2

References/Citations:

1) Guerrero et al. (2011), Probe Development Efforts for an Allosteric Agonist of Sphingosine 1-phosphate Receptor 3 (S1P3); Probe Reports from the NIH Molecular Libraries Program
2) Jo et al. (2012), Novel Selective Allosteric and Bitopic Ligands for the S1P3 Receptor; ACS Chem. Biol. 7 1975

CAS:
945128-26-7
Catalog Number:
10-4493
Activity:
Allosteric sphingosine-1-phosphate receptor 3 agonist
Chemical Name:
N,N-Dicyclohexyl-5-cyclopropyl-1,2-oxazole-3-carboxamide
Alternate Name:
ML249
Molecular Weight:
316.44
Molecular Formula:
C19H28N2O2
Solubility:
Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 15 mg/ml).
Physical Properties:
Off-white solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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