DEPMPO | Spin trap

CAS:
157230-67-6
Catalog Number:
10-4502
Activity:
Spin trap
Chemical Name:
5-Diethoxyphosphoryl-5-methyl-1-pyrroline-N-oxide
Molecular Weight:
235.22
Molecular Formula:
C9H18NO4P
Solubility:
Soluble in Water or Ethanol.
Physical Properties:
Pale yellow oil
Purity:
99% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions are not stable. Solutions must be prepared fresh and used within one working day.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
50 mg$95.00
250 mg$375.00

DEPMPO (157230-67-6) is a spin trap capable of detecting oxygen, nitrogen, sulfur and carbon-centered free radicals both in vitro and in vivo. DEPMPO is useful for distinguishing between superoxide-dependent pathways of hydroxyl radical generation, and those that are superoxide independent.

References/Citations:

1) Liu et al. (1999), Evaluation of DEPMPO as a spin trapping agent in biological systems; Free Radic. Biol. Med., 26 714
2) Shi et al. (2005), Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species; Arch. Biochem. Biophys., 437 59
3) Culcasi et al. (2012), EPR spin trapping evaluation of ROS production in human fibroblasts exposed to cerium oxide nanoparticles: evidence for NADPH oxidase and mitochondrial stimulation; Chem. Biol. Interact., 199 161
4) Tampieri et al. (2019), Comment on “Water Soluble Fluorescent Probe with Dual Mitochondria/Lysosome Targetability for Selective Superoxide Detection in Live Cells and in Zebrafish Embryos; ACS Sens. E-pub. Ahead of Print [Focus Citation]

CAS:
157230-67-6
Catalog Number:
10-4502
Activity:
Spin trap
Chemical Name:
5-Diethoxyphosphoryl-5-methyl-1-pyrroline-N-oxide
Molecular Weight:
235.22
Molecular Formula:
C9H18NO4P
Solubility:
Soluble in Water or Ethanol.
Physical Properties:
Pale yellow oil
Purity:
99% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions are not stable. Solutions must be prepared fresh and used within one working day.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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