Difluoromethylornithine HCl | Inhibits polyamine biosynthesis
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 10 mg | $30.00 | ||
| 100 mg | $65.00 |
Difluoromethylornithine HCl (96020-91-6) is a selective inhibitor of ornithine decarboxylase.1 Induces apoptosis in a variety of cells.2 Difluoromethylornithine HCl displays cancer chemopreventive activity.3 Cell permeable. Active in vivo.
References/Citations:
1) Verma et al. (1990), Inhibition of tumor promotion by DL-alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase; Basic Life Sci., 52 195
2) Takahashi et al. (2000), Alpha-difluoromethylornithine induces apoptosis as well as anti-angiogenesis in the inhibition of tumor growth and metastasis in a human gastric cancer model; Int. J. Cancer, 85 243
3) Meyskens et al. (1999), Development of difluoromethylornithine (DFMO) as a chemoprevention agent; Clin. Cancer Res., 5 945
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Difluoromethylornithine HCl (96020-91-6) is a selective inhibitor of ornithine decarboxylase.1 Induces apoptosis in a variety of cells.2 Difluoromethylornithine HCl displays cancer chemopreventive activity.3 Cell permeable. Active in vivo.
References/Citations:
1) Verma et al. (1990), Inhibition of tumor promotion by DL-alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase; Basic Life Sci., 52 195
2) Takahashi et al. (2000), Alpha-difluoromethylornithine induces apoptosis as well as anti-angiogenesis in the inhibition of tumor growth and metastasis in a human gastric cancer model; Int. J. Cancer, 85 243
3) Meyskens et al. (1999), Development of difluoromethylornithine (DFMO) as a chemoprevention agent; Clin. Cancer Res., 5 945
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