Dihydroouabain | Endogenous ouabain-like factor
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 10 mg | $75.00 | ||
| 50 mg | $300.00 |
Dihydroouabain (DHO; 1183-35-3) has been identified as an endogenous ouabain-like effector of sodium-potassium ATPase in mouse1 and human2 adrenal cells. Micromolar to millimolar concentrations of DHO are known to inhibit Na/K pump activity3 and nanomolar concentrations stimulate Na/K pump activity in an isoform-specific manner4.
References/Citations:
- Qazzaz et al. (2000), Secretion of a lactone-hydrogenated ouabain-like effector of sodium, potassium-adenosine triphosphatase activity by adrenal cells; Endocrinology, 141 3200
- El-Masri et al. (2002), Human adrenal cells in culture produce both ouabain-like and dihydroouabain-like factors; Clin. Chem, 48 1720
- Bielen et al. (1992), The kinetics of the inhibition by dihydroouabain of the sodium pump current in single rabbit cardiac Purkinje cells; Naunyn Schmiedbergs Arch. Pharmacol., 345 100
- Gao et al. (2002), Isoform-specific stimulation of cardiac Na/K pumps by nanomolar concentrations of glycosides; J. Gen. Physiol., 119 297
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Dihydroouabain (DHO; 1183-35-3) has been identified as an endogenous ouabain-like effector of sodium-potassium ATPase in mouse1 and human2 adrenal cells. Micromolar to millimolar concentrations of DHO are known to inhibit Na/K pump activity3 and nanomolar concentrations stimulate Na/K pump activity in an isoform-specific manner4.
References/Citations:
- Qazzaz et al. (2000), Secretion of a lactone-hydrogenated ouabain-like effector of sodium, potassium-adenosine triphosphatase activity by adrenal cells; Endocrinology, 141 3200
- El-Masri et al. (2002), Human adrenal cells in culture produce both ouabain-like and dihydroouabain-like factors; Clin. Chem, 48 1720
- Bielen et al. (1992), The kinetics of the inhibition by dihydroouabain of the sodium pump current in single rabbit cardiac Purkinje cells; Naunyn Schmiedbergs Arch. Pharmacol., 345 100
- Gao et al. (2002), Isoform-specific stimulation of cardiac Na/K pumps by nanomolar concentrations of glycosides; J. Gen. Physiol., 119 297
Related products
-
Levetiracetam | Anticonvulsant
From $45.00CAS:102767-28-2Catalog Number:10-2040Activity:AnticonvulsantChemical Name:2(S)-(2-Oxopyrrolidin-1-yl)butyramideMolecular Weight:170.21Molecular Formula:C29H14N2O2Solubility:Soluble in DMSO (up to at least 25 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
iCRT5 | Beta-catenin inhibitor
From $57.00CAS:18623-44-4Catalog Number:10-1371Activity:Beta-catenin inhibitorChemical Name:4-[5-(3,4-Dimethoxy-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-butyric acidMolecular Weight:367.44Molecular Formula:C16H17NO5S2Solubility:Soluble in DMSO (up to 30 mg/ml)Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
Pomalidomide | Cereblon ubiquitination inhibitor
From $50.00CAS:19171-19-8Catalog Number:10-2768Activity:Cereblon ubiquination inhibitorChemical Name:1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline; 3-amino-N-(2,6-dioxo-3-piperidyl)phthalamideMolecular Weight:273.24Molecular Formula:C13H11N3O4Solubility:Soluble in DMSO (up to 50 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
