Doxycycline monohydrate | Broad spectrum antibiotic
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 1 g | $50.00 | ||
| 5 g | $175.00 |
Doxycycline monohydrate (17086-28-1) is a broad-spectrum tetracycline antibiotic.1 Inhibits matrix metalloproteases.2 Promotes wound repair by inhibiting collagen degradation in rat models.3 Displays neuroprotective effects in neurodegenerative diseases.4 Frequently used in doxycycline-controlled transcriptional activation systems for regulation of gene expression in cell culture and organisms.5,6
References/Citations:
- Riond and Riviere (1988), Pharmacology and toxicology of doxycycline; Vet. Hum. Toxicol. 30 431
- Smith et al. (1999), Specificity of inhibition of matrix metalloproteinase activity by doxycycline: Relationship to structure of the enzyme; Arthritis Rheum. 42 1140
- Lamparter et al. (2002), Doxycycline and tissue repair in rats; J. Lab. Clin. Med. 139 295
- Santa-Cecilia et al. (2019), The Neuroprotective Effect of Doxycycline on Neurodegenerative Diseases; Neurotox. Res. 35 981
- Gossin et al. (1995), Transcriptional activation by tetracyclines in mammalian cells; Science 268 1766
- Li et al. (2013), Simple piggyBac transposon-based mammalian cell expression system for inducible protein production; Proc. Natl. Acad. Sci. USA 110 5004
C22H24N2O8·H2O
>98% by HPLC
NMR: (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Doxycycline monohydrate (17086-28-1) is a broad-spectrum tetracycline antibiotic.1 Inhibits matrix metalloproteases.2 Promotes wound repair by inhibiting collagen degradation in rat models.3 Displays neuroprotective effects in neurodegenerative diseases.4 Frequently used in doxycycline-controlled transcriptional activation systems for regulation of gene expression in cell culture and organisms.5,6
References/Citations:
- Riond and Riviere (1988), Pharmacology and toxicology of doxycycline; Vet. Hum. Toxicol. 30 431
- Smith et al. (1999), Specificity of inhibition of matrix metalloproteinase activity by doxycycline: Relationship to structure of the enzyme; Arthritis Rheum. 42 1140
- Lamparter et al. (2002), Doxycycline and tissue repair in rats; J. Lab. Clin. Med. 139 295
- Santa-Cecilia et al. (2019), The Neuroprotective Effect of Doxycycline on Neurodegenerative Diseases; Neurotox. Res. 35 981
- Gossin et al. (1995), Transcriptional activation by tetracyclines in mammalian cells; Science 268 1766
- Li et al. (2013), Simple piggyBac transposon-based mammalian cell expression system for inducible protein production; Proc. Natl. Acad. Sci. USA 110 5004
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