DU-14 | Sulfatase inhibitor

CAS:
186303-55-9
Catalog Number:
10-1187
Activity:
Sulfatase inhibitor
Chemical Name:
(p-O-Sulfamoyl)-N-tetradecanoyl tyramine
Molecular Weight:
426.62
Molecular Formula:
C22H38N2O4S
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Available Options

size :PriceQuantity 
5 mg$72.00
25 mg$288.00

DU-14 (186303-55-9) inhibits steroid sulfatase (IC50=ca. 60 nM). Enhances learning and spatial memory in rats.1 Inhibits proliferation of human MCF-7 breast cancer cells.2

References/Citations:

1) Johnson et al. (2000), The effect of steroid sulfatase inhibition on learning and spatial memory; Brain Res., 865 286
2) Selcer et al. (1997), Inhibition of estrone sulfatase and proliferation of human breast cancer cells by nonsteroidal (p-O-sulfamoyl)-N-alkanoyl tyramines; Cancer Res., 57 702

CAS:
186303-55-9
Catalog Number:
10-1187
Activity:
Sulfatase inhibitor
Chemical Name:
(p-O-Sulfamoyl)-N-tetradecanoyl tyramine
Molecular Weight:
426.62
Molecular Formula:
C22H38N2O4S
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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