Elastatinal | Elastase inhibitor

CAS:
51798-45-9
Catalog Number:
10-2818
Activity:
Elastase inhibitor
Chemical Name:
N[(S)-1-Carboxyisopentyl]carbamoyl-a-[2-iminohexahydro-4(S)-pyrimidyl-(S)-glycl-(S)-glutaminyl-(S)-alaninal
Molecular Weight:
512.56
Molecular Formula:
C21H36N8O7
Solubility:
Soluble in DMSO (up to 3 mg/ml) or in Water (up to 5 mg/ml)
Physical Properties:
Lyophilized off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
5 mg$75.00
25 mg$318.00
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Elastatinal (51798-45-9) is an irreversible inhibitor of neutrophil elastase.1 Inhibits rat microglia elastase.2 Inhibits the protease activity of poliovirus and rhinovirus 2A proteinase.3 Inhibits the α 2-macroglobulin-protease complex of mouse mammary tumor virus.4

References/Citations:

1) Umezawa et al. (1973), Letter: Elastatinal, a new elastase inhibitor produced by actinomycetes; J. Antibiotics, 26 787
2) Nakajima et al. (1992), Identification of elastase as a secretory protease from cultured rat microglia; J. Neurochem., 58 1401
3) Molla et al. (1993), Inhibition of proteolytic activity of poliovirus and rhinovirus 2A proteases by elastase-specific inhibitors; J. Virol., 67 4688
4) Menendez-Arias et al. (1992), Isolation and characterization of alpha 2-macroglobulin-protease complexes from purified mouse mammary tumor virus and culture supernatants from virus-infected cell lines; J. Biol. Chem., 267 11392

CAS:
51798-45-9
Catalog Number:
10-2818
Activity:
Elastase inhibitor
Chemical Name:
N[(S)-1-Carboxyisopentyl]carbamoyl-a-[2-iminohexahydro-4(S)-pyrimidyl-(S)-glycl-(S)-glutaminyl-(S)-alaninal
Molecular Weight:
512.56
Molecular Formula:
C21H36N8O7
Solubility:
Soluble in DMSO (up to 3 mg/ml) or in Water (up to 5 mg/ml)
Physical Properties:
Lyophilized off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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