Enzalutamide | Non-steroidal antiandrogen
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 10 mg | $40.00 | ||
| 50 mg | $125.00 |
Enzalutamide (915087-33-1) is a clinically useful non-steroidal antiandrogen (IC50 = 36 nM) for the treatment of castration-resistant prostate cancer.1,2 It impairs binding of the androgen receptor to DNA, the recruitment of co-activators, and reduces the efficiency of nuclear translocation.
References:
- Tran et al. (2009), Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer; Science 324 787
- Jung et al. (2010), Structure-Activity Relationship for Thiohydantoin Androgen Receptor Antagonist for Castration-Resistant Prostate Cancer (CRPC); J. Med. Chem. 53 2779
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Enzalutamide (915087-33-1) is a clinically useful non-steroidal antiandrogen (IC50 = 36 nM) for the treatment of castration-resistant prostate cancer.1,2 It impairs binding of the androgen receptor to DNA, the recruitment of co-activators, and reduces the efficiency of nuclear translocation.
References:
- Tran et al. (2009), Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer; Science 324 787
- Jung et al. (2010), Structure-Activity Relationship for Thiohydantoin Androgen Receptor Antagonist for Castration-Resistant Prostate Cancer (CRPC); J. Med. Chem. 53 2779
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