Etoposide | Topoisomerase II inhibitor
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 100 mg | $50.00 | ||
| 500 mg | $160.00 |
Etoposide (33419-42-0) is a chemotherapeutic agent that forms a ternary complex with DNA and topoisomerase II, preventing re-ligation of DNA strands causing DNA cleavage. Etoposide blocks the cell cycle in S-phase and G2-phase.
References/Citations:
1) Hande (1998) Etoposide: four decades of development of a topoisomerase II inhibitor; Eur. J. Cancer 34 1514
2) Smith et.al. (1994) Etoposide-induced cell cycle delay and arrest-dependent modulation of DNA topoisomerase II in small-cell lung cancer cells; Br. J. Cancer. 70 914
NMR (Conforms)
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Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Etoposide (33419-42-0) is a chemotherapeutic agent that forms a ternary complex with DNA and topoisomerase II, preventing re-ligation of DNA strands causing DNA cleavage. Etoposide blocks the cell cycle in S-phase and G2-phase.
References/Citations:
1) Hande (1998) Etoposide: four decades of development of a topoisomerase II inhibitor; Eur. J. Cancer 34 1514
2) Smith et.al. (1994) Etoposide-induced cell cycle delay and arrest-dependent modulation of DNA topoisomerase II in small-cell lung cancer cells; Br. J. Cancer. 70 914
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