Felodipine | L-type Ca channel blocker
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 10 mg | $50.00 | ||
| 50 mg | $120.00 |
Felodipine (72509-76-3) is a potent L-type Ca2+ channel blocker that is selective over N-, R-, P/Q- and T-type channels.1,2 It displays high vascular selectivity over cardiac muscle, thus lowering arterial blood pressure without altering cardiac contractility. Felodipine is used in the clinic as an antihypertensive agent.
References/Citations:
1) Todd and Faulds, (1992) Felodipine. A review of the pharmacology and therapeutic use of the extended release formulation in cardiovascular disorders; Drugs 44 251
2) Furukawa et al. (1999) Selectivities of Dihydropyridine Derivatives in Blocking Ca2+ Channel Subtypes Expressed in Xenopus Oocytes; J. Pharmacol. Exp. Ther. 291 464
NMR (Conforms)
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Product Data Sheet:
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Felodipine (72509-76-3) is a potent L-type Ca2+ channel blocker that is selective over N-, R-, P/Q- and T-type channels.1,2 It displays high vascular selectivity over cardiac muscle, thus lowering arterial blood pressure without altering cardiac contractility. Felodipine is used in the clinic as an antihypertensive agent.
References/Citations:
1) Todd and Faulds, (1992) Felodipine. A review of the pharmacology and therapeutic use of the extended release formulation in cardiovascular disorders; Drugs 44 251
2) Furukawa et al. (1999) Selectivities of Dihydropyridine Derivatives in Blocking Ca2+ Channel Subtypes Expressed in Xenopus Oocytes; J. Pharmacol. Exp. Ther. 291 464
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