Size : | Price | Quantity | |
---|---|---|---|
1 mg | $130.00 | ||
5 mg | $500.00 |
Filipin III (480-49-9) is a polyene macrolide antibiotic. It may be used in a double staining procedure for the detection of lipoproteins.1 Binds specifically to cholesterol forming a fluorescent complex which may be used for staining.2 Disrupts the lipid raft/caveolae endocytosis pathway.3 Prevents pathological prion protein accumulation by reducing endocytosis and inducing cellular PrP release.4
References/Citations:
1) Smejkal and Hof (1994), Cholesterol-specific probe for lipoproteins immobilized on nitrocellulose membranes; Biotechniques, 16 68
2) Bornig and Geyer (1974), Staining of cholesterol with the fluorescent antibiotic “filipin”; Acta Histochemica, 50 110
3) Huo et al. (2003), Lipid rafts/caveolae are essential for insulin-like growth factor-1 receptor signaling during 3T3-L1 preadipocyte differentiation induction; J. Biol. Chem., 278 11561
4) Marella et al. (2002), Filipin prevents pathological prion protein accumulation by reducing endocytosis and inducing cellular PrP release; J. Biol. Chem., 277 25457
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Filipin III (480-49-9) is a polyene macrolide antibiotic. It may be used in a double staining procedure for the detection of lipoproteins.1 Binds specifically to cholesterol forming a fluorescent complex which may be used for staining.2 Disrupts the lipid raft/caveolae endocytosis pathway.3 Prevents pathological prion protein accumulation by reducing endocytosis and inducing cellular PrP release.4
References/Citations:
1) Smejkal and Hof (1994), Cholesterol-specific probe for lipoproteins immobilized on nitrocellulose membranes; Biotechniques, 16 68
2) Bornig and Geyer (1974), Staining of cholesterol with the fluorescent antibiotic “filipin”; Acta Histochemica, 50 110
3) Huo et al. (2003), Lipid rafts/caveolae are essential for insulin-like growth factor-1 receptor signaling during 3T3-L1 preadipocyte differentiation induction; J. Biol. Chem., 278 11561
4) Marella et al. (2002), Filipin prevents pathological prion protein accumulation by reducing endocytosis and inducing cellular PrP release; J. Biol. Chem., 277 25457
t-Butyl 2-[(4-propan-2-yloxybenzoyl)amino]-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-5-carboxylate
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