Fumagillin | MetAP-2 inhibitor
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 1 mg | $75.00 | ||
| 5 mg | $290.00 |
Fumagillin (23110-15-8) is a natural product isolated from the microbial organism Aspergillus fumigatus and used as an antimicrobial for honey bees. It covalently binds and inhibits methionine aminopeptidase-2.1 Fumagillin also inhibits endothelial cell proliferation in vitro and tumor-induced angiogenesis in vivo.2
References/Citations:
1) Sin et al. (1997) The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2; Proc. Natl. Acad. Sci. USA, 94 6099
2) Ingber et al. (1990) Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth; Nature, 348 555
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Fumagillin (23110-15-8) is a natural product isolated from the microbial organism Aspergillus fumigatus and used as an antimicrobial for honey bees. It covalently binds and inhibits methionine aminopeptidase-2.1 Fumagillin also inhibits endothelial cell proliferation in vitro and tumor-induced angiogenesis in vivo.2
References/Citations:
1) Sin et al. (1997) The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2; Proc. Natl. Acad. Sci. USA, 94 6099
2) Ingber et al. (1990) Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth; Nature, 348 555
Related products
-
Herbimycin A | HSP90 Inhibitor
From $90.00CAS:70563-58-5Catalog Number:10-2567Activity:HSP90 InhibitorChemical Name:(15R)-17-Demethoxy-15 methoxy-11-O-methyl-geldanamycinMolecular Weight:574.68Molecular Formula:C30H42N2O9Solubility:Soluble in DMSO (up to 6 mg/ml).Physical Properties:Yellow lyophilized solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
17-AAG | HSP90 inhibitor
From $35.00CAS:75747-14-7Catalog Number:10-1097Activity:HSP90 inhibitorChemical Name:17-(Allylamino)-17-desmethoxygeldanamycinMolecular Weight:585.7Molecular Formula:C31H43N3O8Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 5 mg/ml).Physical Properties:Purple or dark red solidPurity:>98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Thalidomide | E3 UB ligase inhibitor
From $50.00CAS:50-35-1Catalog Number:10-1115Activity:E3 UB ligase inhibitorChemical Name:N-(2,6-Dioxo-3-piperidinyl)phthalimide, racemicMolecular Weight:258.25Molecular Formula:C13H10N2O4Solubility:Soluble in DMSO (up to 5 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
