Gabapentin | Neuropathic pain drug
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 25 mg | $55.00 | ||
| 100 mg | $200.00 |
Gabapentin (60142-96-3) is an approved drug for treatment of various types of neuropathic pain and some forms of epilepsy. The mechanism of action of gabapentin is not well understood. Despite being a structural mimic of GABA, it does not bind to GABA receptors at concentrations up to 1 mM.1,2 Some of its actions may be due to disrupting calcium channels.3
References/Citations:
1) Cheng et al. (2004), Does gabapentin act as an agonist at native GABA(B) receptors?; J. Biomed. Sci., 11 346
2) Lanneau et al. (2001), Gabapentin is not a GABAB receptor agonist; Neuropharmacology 41 965
3) Hendrich et al. (2008), Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin; Proc. Natl. Acad. Sci. USA, 105 3628
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
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Gabapentin (60142-96-3) is an approved drug for treatment of various types of neuropathic pain and some forms of epilepsy. The mechanism of action of gabapentin is not well understood. Despite being a structural mimic of GABA, it does not bind to GABA receptors at concentrations up to 1 mM.1,2 Some of its actions may be due to disrupting calcium channels.3
References/Citations:
1) Cheng et al. (2004), Does gabapentin act as an agonist at native GABA(B) receptors?; J. Biomed. Sci., 11 346
2) Lanneau et al. (2001), Gabapentin is not a GABAB receptor agonist; Neuropharmacology 41 965
3) Hendrich et al. (2008), Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin; Proc. Natl. Acad. Sci. USA, 105 3628
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