Genistein | Genistin aglycone
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 100 mg | $30.00 | ||
| 500 mg | $80.00 |
Genistein (446-72-0) is a naturally occurring flavonoid with a wide range of biological actions. Inhibits protein tyrosine kinases including epidermal growth factor receptor kinase.1,2 Phytoestrogen3 and agonist at GPR304. Displays cancer chemopreventive activity.5
References/Citations
1) Akiyama et al. (1987), Genistein, a specific inhibitor of tyrosine-specific protein kinases; J. Biol. Chem., 262 5592
2) Linassier et al. (1990), Mechanisms of action in NIH-3T3 cells of genistein, an inhibitor if EGF receptor tyrosine kinase Biochem. Pharmacol., 39 187
3) Dang et al. (2003), Peroxisome proliferator-activated receptor gamma (PPARgamma) as a molecular target for the soy phytoestrogen genistein; J. Biol. Chem., 278 962
4) Vivacqua et al. (2006), 17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30; Mol. Pharmacol., 70 1414
5) Sarker and Li (2002), Mechanisms of cancer chemoprevention by soy isoflavone genistein; Cancer Metastasis Rev., 21 265
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Genistein (446-72-0) is a naturally occurring flavonoid with a wide range of biological actions. Inhibits protein tyrosine kinases including epidermal growth factor receptor kinase.1,2 Phytoestrogen3 and agonist at GPR304. Displays cancer chemopreventive activity.5
References/Citations
1) Akiyama et al. (1987), Genistein, a specific inhibitor of tyrosine-specific protein kinases; J. Biol. Chem., 262 5592
2) Linassier et al. (1990), Mechanisms of action in NIH-3T3 cells of genistein, an inhibitor if EGF receptor tyrosine kinase Biochem. Pharmacol., 39 187
3) Dang et al. (2003), Peroxisome proliferator-activated receptor gamma (PPARgamma) as a molecular target for the soy phytoestrogen genistein; J. Biol. Chem., 278 962
4) Vivacqua et al. (2006), 17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30; Mol. Pharmacol., 70 1414
5) Sarker and Li (2002), Mechanisms of cancer chemoprevention by soy isoflavone genistein; Cancer Metastasis Rev., 21 265
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