GRL-0496 | SARS-CoV 3CLpro inhibitor

CAS:
1087243-14-8
Catalog Number:
10-4960
Activity:
SARS-CoV 3CLpro inhibitor
Chemical Name:
1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester
Molecular Weight:
272.69
Molecular Formula:
C14H9ClN2O2
Solubility:
Soluble in DMSO (>30 mg/mL) and ethanol (>25 mg/mL)
Physical Properties:
White solid
Purity:
>98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
5 mg$60.00
25 mg$225.00

GRL-0496 (1087243-14-8) is a potent (IC50 = 30 nM in cell culture assays) inhibitor of severe acute respiratory syndrome-coronavirus chymotrypsin-like protease (SARS-CoV 3CLpro).1

References/Citations:

1)    Ghosh et al. (2008), Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors; Bioorg. Med. Chem.Lett, 18 5684

CAS:
1087243-14-8
Catalog Number:
10-4960
Activity:
SARS-CoV 3CLpro inhibitor
Chemical Name:
1H-Indole-4-carboxylic acid, 5-chloro-3-pyridinyl ester
Molecular Weight:
272.69
Molecular Formula:
C14H9ClN2O2
Solubility:
Soluble in DMSO (>30 mg/mL) and ethanol (>25 mg/mL)
Physical Properties:
White solid
Purity:
>98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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