GSK-3787 | PPARδ antagonist
CAS:
188591-46-0
Catalog Number:
10-1001
Activity:
PPARδ antagonist
Chemical Names:
4-Chloro-N-(2-{[5-(trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide
Molecular Weight:
392.78
Molecular Formula:
C15H12ClF3N2O3S
Solubility:
Soluble in DMSO (30 mg/ml)
Physical Properties:
White solid
Purity:
98% TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year for up to year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $50.00 | ||
| 25 mg | $200.00 |
This product is also available in the following library:
GSK-3787 (188591-46-0) is a selective and irreversible antagonist of the peroxisome proliferator-activated receptor δ (PPARδ) – plC50 = 6.6. It covalently binds to Cys 249 in the PPARd binding site.
References:
- Shearer et al., (2010) Identification and characterization of 4-chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonist; J. Med. Chem. 53 1857
- Palkar et al (2010) Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-β/δ antagonist GSK3787; Mol.Pharmacol. 78 419
CAS:
188591-46-0
Catalog Number:
10-1001
Activity:
PPARδ antagonist
Chemical Names:
4-Chloro-N-(2-{[5-(trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide
Molecular Weight:
392.78
Molecular Formula:
C15H12ClF3N2O3S
Solubility:
Soluble in DMSO (30 mg/ml)
Physical Properties:
White solid
Purity:
98% TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year for up to year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Safety Data Sheet:
N/A
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
GSK-3787 (188591-46-0) is a selective and irreversible antagonist of the peroxisome proliferator-activated receptor δ (PPARδ) – plC50 = 6.6. It covalently binds to Cys 249 in the PPARd binding site.
References:
- Shearer et al., (2010) Identification and characterization of 4-chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonist; J. Med. Chem. 53 1857
- Palkar et al (2010) Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-β/δ antagonist GSK3787; Mol.Pharmacol. 78 419
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21
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Plymouth Meeting, PA USA
1-855-FOCUS21
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