GSK-690693 HCl | Akt inhibitor
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $98.00 | ||
| 25 mg | $340.00 |
GSK-690693 (937174-76-0) is a novel ATP-competitive pan-specific Akt kinase inhibitor. (IC50‘s=2, 13, 9 nM for Akt1, 2 and 3 respectively) Antitumor activity. Active in vivo. GSK-690693 induces hyperglycemia. Cell permeable.
References/Citations:
1) Rhodes et al. (2008), Characterization of an Akt kinase inhibitor with potent pharmacodynamics and antitumor activity; Cancer Res., 68 2366
2) Crouthamel et al. (2009), Mechanism and management of AKT inhibitor-induced hyperglycemia; Clin. Cancer Res., 15 217
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
GSK-690693 (937174-76-0) is a novel ATP-competitive pan-specific Akt kinase inhibitor. (IC50‘s=2, 13, 9 nM for Akt1, 2 and 3 respectively) Antitumor activity. Active in vivo. GSK-690693 induces hyperglycemia. Cell permeable.
References/Citations:
1) Rhodes et al. (2008), Characterization of an Akt kinase inhibitor with potent pharmacodynamics and antitumor activity; Cancer Res., 68 2366
2) Crouthamel et al. (2009), Mechanism and management of AKT inhibitor-induced hyperglycemia; Clin. Cancer Res., 15 217
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