GSK-690693 HCl | Akt inhibitor
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $98.00 | ||
| 25 mg | $340.00 |
GSK-690693 (937174-76-0) is a novel ATP-competitive pan-specific Akt kinase inhibitor. (IC50‘s=2, 13, 9 nM for Akt1, 2 and 3 respectively) Antitumor activity. Active in vivo. GSK-690693 induces hyperglycemia. Cell permeable.
References/Citations:
1) Rhodes et al. (2008), Characterization of an Akt kinase inhibitor with potent pharmacodynamics and antitumor activity; Cancer Res., 68 2366
2) Crouthamel et al. (2009), Mechanism and management of AKT inhibitor-induced hyperglycemia; Clin. Cancer Res., 15 217
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
GSK-690693 (937174-76-0) is a novel ATP-competitive pan-specific Akt kinase inhibitor. (IC50‘s=2, 13, 9 nM for Akt1, 2 and 3 respectively) Antitumor activity. Active in vivo. GSK-690693 induces hyperglycemia. Cell permeable.
References/Citations:
1) Rhodes et al. (2008), Characterization of an Akt kinase inhibitor with potent pharmacodynamics and antitumor activity; Cancer Res., 68 2366
2) Crouthamel et al. (2009), Mechanism and management of AKT inhibitor-induced hyperglycemia; Clin. Cancer Res., 15 217
Related products
-
AG-1296 | PDGFR kinase inhibitor
From $60.00CAS:146535-11-7Catalog Number:10-1087Activity:PDGFR kinase inhibitorChemical Name:6,7-Dimethoxy-3-phenylquinoxalineMolecular Weight:266.3Molecular Formula:C16H14N2O2Solubility:Soluble in DMSO.Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Adapalene | Retinoid RARbeta, gamma agonist
From $30.00CAS:106685-40-9Catalog Number:10-1011Activity:Retinoid RARβ,γ agonistAlternate Names:CD271Chemical Name:6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthoic acidMolecular Weight:412.53Molecular Formula:C28H28O3Solubility:Soluble in DMSO (up to 3 mg/ml) or in DMF (up to 6 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 monthsShipping Code:RT -
LFM-A13 | BTK inhibitor
From $55.00CAS:244240-24-2Catalog Number:10-1032Activity:BTK inhibitorChemical Name:(2Z)-2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamideMolecular Weight:360Molecular Formula:C11H8Br2N2O2Solubility:Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 15 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. PROTECT FROM MOISTURE. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
