GYY4137 | Hydrogen sulfide donor

CAS:
106740-09-4
Catalog Number:
10-4507
Activity:
Hydrogen sulfide donor
Chemical Names:
Morpholine (4-methoxyphenyl)(morpholino)phosphinodithioate
Molecular Weight:
376.47
Molecular Formula:
C15H25N2O3PS2
Solubility:
Soluble in DMSO (>25 mg/ml); Water (25 mg/ml)
Physical Properties:
White solid
Purity:
99% NMR
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Make solutions fresh daily – GYY4137 starts to react immediately with water.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
10 mg$45.00
50 mg$165.00

GYY4137 (106740-09-4) is a water soluble hydrogen sulfide slow-releasing molecule.1 Rate of release at pH 7.4 and 37°C was 4.17 ± 0.5 nmol/25 min. Release rate is both pH and temperature dependent.  It displays vasodilatory, anti-hypertensive, cardioprotective, anti-inflammatory, and anticancer effects.2

References/Citations:

  1. Li et al. (2008), Characterization of a novel, water-soluble hydrogen sulfide-releasing molecules (GYY4137): new insights into the biology of hydrogen sulfide; Circulation 117 2351
  2. Nin et al. (2020), Biological Effects of Morpholin-4-Ium 4-Methoxyphenyl(Morpholino)Phosphinodithioate and Other Phosphorothioate-Based Hydrogen Sulfide Donors; Antioxid. Redox. Signal. 32 145
CAS:
106740-09-4
Catalog Number:
10-4507
Activity:
Hydrogen sulfide donor
Chemical Names:
Morpholine (4-methoxyphenyl)(morpholino)phosphinodithioate
Molecular Weight:
376.47
Molecular Formula:
C15H25N2O3PS2
Solubility:
Soluble in DMSO (>25 mg/ml); Water (25 mg/ml)
Physical Properties:
White solid
Purity:
99% NMR
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Make solutions fresh daily – GYY4137 starts to react immediately with water.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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