Hypericin | Protein kinase C inhibitor

CAS:
548-04-9
Catalog Number:
10-2077
Activity:
Protein kinase C inhibitor
Chemical Name:
1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione
Molecular Weight:
504.45
Molecular Formula:
C30H16O8
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml).
Physical Properties:
Brown solid
Purity:
>98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

size :PriceQuantity 
1 mg$58.00
10 mg$395.00

Hypericin (548-04-9) is a natural product found in St. John’s Wort (Hypericum perforatum). A multifunctional agent that has been reported to be antidepressive, antineoplastic, antitumor and antiviral. Inhibitory effects have been demonstrated on various enzyme including MAO, PKC, dopamine-β-hydroxylase, reverse transcriptase, telomerase and CYP.1 Hypericin can cause photosensitivity – as a result, it is being investigated as an agent in photodynamic therapy.2

References/Citations:

1) Kubin et al., (2005) Hypericin – the facts about a controversial agent; Current Pharm. Des., 11 233
2) Theodossiou et al., (2009) The multifaceted photocytotoxic profile of hypericin; Mol. Pharmacol., 6 1775

CAS:
548-04-9
Catalog Number:
10-2077
Activity:
Protein kinase C inhibitor
Chemical Name:
1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione
Molecular Weight:
504.45
Molecular Formula:
C30H16O8
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml).
Physical Properties:
Brown solid
Purity:
>98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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