Ibandronate | Farnesyl pyrophosphatase synthase inhibitor / osteoporosis drug

CAS:
138926-19-9
Catalog Number:
10-4630
Activity:
Farnesyl pyrophosphatase synthase inhibitor / osteoporosis drug
Chemical Name:
(1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid sodium monohydrate
Molecular Weight:
359.23
Molecular Formula:
C9H22NO7P2•Na • H2O
Solubility:
Soluble in DMSO (up to at least 25 mg/ml)
Physical Properties:
White solid
Purity:
98%
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
50 mg$30.00
250 mg$100.00

Ibandronate (138926-19-9) is a clinically useful drug for the prevention and treatment of osteoporosis and skeletal fractures in patients with cancer.  It is a potent inhibitor of farnesyl pyrophosphate synthase (IC50 = 20 nM) and strongly binds to hydroxyapatite.1

References/Citations:

1) Russell (2006), Ibandronate: Pharmacology and preclinical studies; Bone 38 S7

CAS:
138926-19-9
Catalog Number:
10-4630
Activity:
Farnesyl pyrophosphatase synthase inhibitor / osteoporosis drug
Chemical Name:
(1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid sodium monohydrate
Molecular Weight:
359.23
Molecular Formula:
C9H22NO7P2•Na • H2O
Solubility:
Soluble in DMSO (up to at least 25 mg/ml)
Physical Properties:
White solid
Purity:
98%
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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