IDE2 | Inducer of Definitive Endoderm
Available Options
| Size | Price | Quantity | |
|---|---|---|---|
| 5mg | $80.00 | ||
| 25mg | $295.00 |
IDE2 (1136466-93-7) induces robust differentiation of embryonic stem cells into endoderm (EC50 = 223 nM) in both mouse and human cells via activation of the TGFß signaling pathway.1 It was able to induce definitive endoderm in mouse embryonic stem cells in a protocol to create lung alveolar epithelial cells.2
References/Citations:
- Borowiak et al. (2009) Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells; Cell Stem Cell, 4 348
- Dezfouli et al. (2019) Hydrocortisone Promotes Differentiation of Mouse Embryonic Stem Cell-Derived Definitive Endoderm toward Lung Alveolar Epithelial Cells; Cell J. 20 469
C12H20N2O3
>98% HPLC
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
IDE2 (1136466-93-7) induces robust differentiation of embryonic stem cells into endoderm (EC50 = 223 nM) in both mouse and human cells via activation of the TGFß signaling pathway.1 It was able to induce definitive endoderm in mouse embryonic stem cells in a protocol to create lung alveolar epithelial cells.2
References/Citations:
- Borowiak et al. (2009) Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells; Cell Stem Cell, 4 348
- Dezfouli et al. (2019) Hydrocortisone Promotes Differentiation of Mouse Embryonic Stem Cell-Derived Definitive Endoderm toward Lung Alveolar Epithelial Cells; Cell J. 20 469
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