iFSP1 | FSP1 inhibitor
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $40.00 | ||
| 25 mg | $160.00 |
iFSP1 (150651-39-1) inhibits ferroptosis suppressor protein 1, inducing ferroptosis.1 iFSP1 synergizes with GPX4 inhibitors to initiate ferroptosis in cancer cells.1 It potently induced ferroptosis, which promoted innate and adaptive anti-tumor immune responses, in human hepatocellular carcinoma cells which overexpress FSP1.2 A useful tool for establishing ferroptotic cells in Alzheimer’s disease models.3
References/Citations:
- Doll et al. (2019), FSP1 is a glutathione-independent ferroptosis suppressor; Nature 575 693
- Cheu et al. (2023), Ferroptosis Suppressor Protein 1 Inhibition Promotes Tumor Ferroptosis and Anti-tumor Immune Responses in Liver Cancer; Cell Mol. Gastroenterol. Hepatol. 16 133
- Yong et al. (2024), Penthorum chinense Pursh inhibits ferroptosis in cellular and Caenorhabditis elegans models of Alzheimer’s disease; Phytomedicine 127 155463
C20H13N6
>98% TLC
NMR: (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
iFSP1 (150651-39-1) inhibits ferroptosis suppressor protein 1, inducing ferroptosis.1 iFSP1 synergizes with GPX4 inhibitors to initiate ferroptosis in cancer cells.1 It potently induced ferroptosis, which promoted innate and adaptive anti-tumor immune responses, in human hepatocellular carcinoma cells which overexpress FSP1.2 A useful tool for establishing ferroptotic cells in Alzheimer’s disease models.3
References/Citations:
- Doll et al. (2019), FSP1 is a glutathione-independent ferroptosis suppressor; Nature 575 693
- Cheu et al. (2023), Ferroptosis Suppressor Protein 1 Inhibition Promotes Tumor Ferroptosis and Anti-tumor Immune Responses in Liver Cancer; Cell Mol. Gastroenterol. Hepatol. 16 133
- Yong et al. (2024), Penthorum chinense Pursh inhibits ferroptosis in cellular and Caenorhabditis elegans models of Alzheimer’s disease; Phytomedicine 127 155463
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