iGP-1 | Mitochondrial GPDH inhibitor

CAS:
27031-00-1
Catalog Number:
10-4747
Activity:
Mitochondrial GPDH inhibitor
Chemical Name:
N-[4-(1H-Benzoimidazol-2-yl)-phenyl]-succinamic acid
Molecular Weight:
309.32
Molecular Formula:
C17H15N3O3
Solubility:
Soluble in DMSO (up to 50 mg/ml).
Physical Properties:
Beige solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
5 mg$50.00
25 mg$180.00
This product is also available in the following library:

iGP-1 (27031-00-1) is a potent and cell permeable inhibitor of mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH), IC50=6.3 μM, that is selective over the cytosolic enzyme1. It does not block pyruvate uptake into cells or mitochondria and has no direct effect on glycolysis in synaptosomes. This novel inhibitor is a unique tool which may be used to investigate the role of glycerol-3-phosphate metabolism in isolated and intact systems.1

References/Citations:

1) Orr et al. (2014), Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase; PLoS One, 9 e89938

CAS:
27031-00-1
Catalog Number:
10-4747
Activity:
Mitochondrial GPDH inhibitor
Chemical Name:
N-[4-(1H-Benzoimidazol-2-yl)-phenyl]-succinamic acid
Molecular Weight:
309.32
Molecular Formula:
C17H15N3O3
Solubility:
Soluble in DMSO (up to 50 mg/ml).
Physical Properties:
Beige solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

20% OFF

For Postdoc
Customers!