IMP-1700 | Bacterial DNA repair inhibitor
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 10 mg | $60.00 | ||
| 50 mg | $195.00 |
IMP-1700 (1458674-25-3) is a potent inhibitor of the bacterial DNA double-strand break repair complex AddAB. It is capable of synergistic sensitization of methicillin-resistant staphylococcus aureus (MRSA) to ciprofloxacin (EC50 = 0.6nM). IMP-1700 is an important new tool for exploring new treatment options for drug resistant bacteria.
References/Citations:
1) Lim et al. (2019), Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus; Bioorg. Med. Chem., 27 114962
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
IMP-1700 (1458674-25-3) is a potent inhibitor of the bacterial DNA double-strand break repair complex AddAB. It is capable of synergistic sensitization of methicillin-resistant staphylococcus aureus (MRSA) to ciprofloxacin (EC50 = 0.6nM). IMP-1700 is an important new tool for exploring new treatment options for drug resistant bacteria.
References/Citations:
1) Lim et al. (2019), Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus; Bioorg. Med. Chem., 27 114962
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