IMP-1700 | Bacterial DNA repair inhibitor
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 10 mg | $60.00 | ||
| 50 mg | $195.00 |
IMP-1700 (1458674-25-3) is a potent inhibitor of the bacterial DNA double-strand break repair complex AddAB. It is capable of synergistic sensitization of methicillin-resistant staphylococcus aureus (MRSA) to ciprofloxacin (EC50 = 0.6nM). IMP-1700 is an important new tool for exploring new treatment options for drug resistant bacteria.
References/Citations:
1) Lim et al. (2019), Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus; Bioorg. Med. Chem., 27 114962
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
IMP-1700 (1458674-25-3) is a potent inhibitor of the bacterial DNA double-strand break repair complex AddAB. It is capable of synergistic sensitization of methicillin-resistant staphylococcus aureus (MRSA) to ciprofloxacin (EC50 = 0.6nM). IMP-1700 is an important new tool for exploring new treatment options for drug resistant bacteria.
References/Citations:
1) Lim et al. (2019), Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus; Bioorg. Med. Chem., 27 114962
Related products
-
Puromycin | Translation inhibitor
From $50.00CAS:58-58-2Catalog Number:10-2100Activity:Translation inhibitorChemical Name:(S)-3′-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]-amino]-3′-deoxy-N,N-dimethyl-adenosine dihydrochlorideMolecular Weight:544.43Molecular Formula:C22H29N7O5 2HClSolubility:Soluble in DMSO (up to 50 mg/ml), or in Water (up to 50 mg/ml).Physical Properties:Tan solidPurity:98%
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.Shipping Code:RT -
Blasticidin S HCl | Antibiotic selection agent
From $80.00CAS:3513-03-9Catalog Number:10-2830Activity:Blasticidin S HClChemical Name:(S)-4-[[3-Amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-β-D-erythro-hex-2-enopyranuronic acid hydrochlorideMolecular Weight:458.90Molecular Formula:C17H26N8O5 &bul; HClSolubility:Soluble in Water (greater than 25 mg/ml)Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.Shipping Code:RT -
Antibiotic A-23187 | Ca2+ ionophore
From $70.00CAS:52665-69-7Catalog Number:10-2284Activity:Ca2+ ionophoreAlternate Names:CalcimycinMolecular Weight:523.62Molecular Formula:C29H37N3O6Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml).Physical Properties:Off-white solidPurity:98%Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 4 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
