IPBT-5CA | GPR109B agonist

CAS:
306935-41-1
Catalog Number:
10-1070
Activity:
GPR109B agonist
Alternate Names:
IBC-293
Chemical Name:
1-(1-Methylethyl)-1H-benzotriazole-5-carboxylic acid
Molecular Weight:
205.22
Molecular Formula:
C10H11N2O2
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
10 mg$35.00
50 mg$75.00

IPBT-5CA (306935-41-1) is a highly selective agonist for the human orphan G-protein-coupled receptor GPR109b (EC50 = 400 nM). No activity was reported at the highly homologous high-affinity niacin receptor GPR109a.

References/Citations:

1) Semple et al. (2006) 1-Alkyl-benzotriazole-5-carboxylic acids are highly selective agonists of the human orphan G-protein-coupled receptor GPR109b; J. Med. Chem., 49 1227

CAS:
306935-41-1
Catalog Number:
10-1070
Activity:
GPR109B agonist
Alternate Names:
IBC-293
Chemical Name:
1-(1-Methylethyl)-1H-benzotriazole-5-carboxylic acid
Molecular Weight:
205.22
Molecular Formula:
C10H11N2O2
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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