Ivabradine HCl | Heart failure / unstable angina drug
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 10 mg | $60.00 | ||
| 50 mg | $220.00 |
Ivabradine (148849-67-6) is a clinically useful heart failure and chronic unstable angina medication.1 It lowers heart rate via inhibition of hyperpolarization-activated cyclic nucleotide-gated channels (HCN) expressed in the sinoatrial node (IC50’s: HCN1 = 2.05 µM, HCN2 = 2.29 µM, HCN3 = 2.51 µM, HCN4 = 2.15 µM).2
References/Citations
1) Ide et al. (2019), Ivabradine for the Treatment of Cardiovascular Diseases; Circ. J. 83 252
2) Stieber et al. (2006), Bradycardic and Proarrhythmic Properties of Sinus Node Inhibitors; Mol. Pharmacol. 69 1328
NMR (Conforms)
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Product Data Sheet:
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Ivabradine (148849-67-6) is a clinically useful heart failure and chronic unstable angina medication.1 It lowers heart rate via inhibition of hyperpolarization-activated cyclic nucleotide-gated channels (HCN) expressed in the sinoatrial node (IC50’s: HCN1 = 2.05 µM, HCN2 = 2.29 µM, HCN3 = 2.51 µM, HCN4 = 2.15 µM).2
References/Citations
1) Ide et al. (2019), Ivabradine for the Treatment of Cardiovascular Diseases; Circ. J. 83 252
2) Stieber et al. (2006), Bradycardic and Proarrhythmic Properties of Sinus Node Inhibitors; Mol. Pharmacol. 69 1328
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