Ivabradine HCl | Heart failure / unstable angina drug
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 10 mg | $60.00 | ||
| 50 mg | $220.00 |
Ivabradine (148849-67-6) is a clinically useful heart failure and chronic unstable angina medication.1 It lowers heart rate via inhibition of hyperpolarization-activated cyclic nucleotide-gated channels (HCN) expressed in the sinoatrial node (IC50’s: HCN1 = 2.05 µM, HCN2 = 2.29 µM, HCN3 = 2.51 µM, HCN4 = 2.15 µM).2
References/Citations
1) Ide et al. (2019), Ivabradine for the Treatment of Cardiovascular Diseases; Circ. J. 83 252
2) Stieber et al. (2006), Bradycardic and Proarrhythmic Properties of Sinus Node Inhibitors; Mol. Pharmacol. 69 1328
NMR (Conforms)
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Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Ivabradine (148849-67-6) is a clinically useful heart failure and chronic unstable angina medication.1 It lowers heart rate via inhibition of hyperpolarization-activated cyclic nucleotide-gated channels (HCN) expressed in the sinoatrial node (IC50’s: HCN1 = 2.05 µM, HCN2 = 2.29 µM, HCN3 = 2.51 µM, HCN4 = 2.15 µM).2
References/Citations
1) Ide et al. (2019), Ivabradine for the Treatment of Cardiovascular Diseases; Circ. J. 83 252
2) Stieber et al. (2006), Bradycardic and Proarrhythmic Properties of Sinus Node Inhibitors; Mol. Pharmacol. 69 1328
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