JX401 | p38α MAP kinase inhibitor

CAS:
349087-34-9
Catalog Number:
10-1022
Activity:
p38α MAP kinase inhibitor
Chemical Name:
1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine
Molecular Weight:
355.49
Molecular Formula:
C21H25NO2S
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. PROTECT FROM MOISTURE. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
10 mg$110.00
50 mg$440.00

JX401 (349087-34-9) is a potent, cell-permeable inhibitor of p38α (IC50 = 32 nM). No inhibition of p38β was observed at 10 μM.

References/Citations:

1) Friedmann et al. (2006), JX401,a p38α inhibitor containing a 4-benzylpiperidine motif, identified via a novel screening system in yeast; Mol. Pharmacol., 70 1395.

CAS:
349087-34-9
Catalog Number:
10-1022
Activity:
p38α MAP kinase inhibitor
Chemical Name:
1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine
Molecular Weight:
355.49
Molecular Formula:
C21H25NO2S
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. PROTECT FROM MOISTURE. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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