K252B | Kinase inhibitor (pan-specific)

CAS:
99570-78-2
Catalog Number:
10-2081
Activity:
Kinase inhibitor (pan-specific)
Molecular Weight:
453.46
Molecular Formula:
C26H19N3O5
Solubility:
Soluble in DMSO (up to 1 mg/ml) or in DMF (up to 1 mg/ml).
Physical Properties:
White or off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

size :PriceQuantity 
100 µg$60.00
1 mg$275.00

K252B (99570-78-2) is a potent pan-specific protein kinase inhibitor: PKA (K= 20 nM), PKG (Ki = 100 nM)1 as well as other kinases. Cell impermeable.2

References/Citations:

1) Kase et al. (1987), K252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases; Biochem. Biophys. Res. Commun., 142 436
2) Makino et al. (2012), Inhibition of uterine sarcoma cell growth through suppression of endogenous tyrosine kinase B signaling; PLoS One, 7 e41049

CAS:
99570-78-2
Catalog Number:
10-2081
Activity:
Kinase inhibitor (pan-specific)
Molecular Weight:
453.46
Molecular Formula:
C26H19N3O5
Solubility:
Soluble in DMSO (up to 1 mg/ml) or in DMF (up to 1 mg/ml).
Physical Properties:
White or off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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