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  • IQ-1S | JNK3 inhibitor
    IQ-1S (1421610-21-0) is a JNK3 inhibitor (Kd = 87, 360 and 390 nM for JNK3, JNK2 and JNK1, respectively). Displays anti-inflammatory and immunosuppresive activity. Inhibits LPS-induced proinflammatory cytokine and nitric...

  • JNK inhibitor IX | JNK inhibitor
    JNK inhibitor IX (312917-14-9) inhibits JNK2 and JNK3 via binding to the ATP binding domain. Displays little or no activity against JNK1, p38α and a panel of 30 other kinases.1 Induces prometaphase arrest-dependent...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of SP-600125 | JNK inhibitor | CAS 129-56-6
    SP-600125 (129-56-6) is a selective inhibitor of c-Jun N-terminal kinase (JNK). Reversibly inhibits JNK1,2 and 3 (IC50's range from 40-90 nM). >300-fold selectivity for JNK as compared to related MAP kinases...

  • SR-3576 | 1164153-22-3 | Structure | Supplier
    SR-3576 (1164153-22-3) is a potent and selective JNK3 inhibitor. IC50 = 7nM and >2800-fold selective over p38.1 Cell permeable. References/Citations 1) Kamenecka et al. (2009), Structure-activity relationships and X-ray...

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