KT5720 | PKA inhibitor

CAS:
108068-98-0
Catalog Number:
10-2082
Activity:
PKA inhibitor
Molecular Weight:
537.62
Molecular Formula:
C32H31N3O5
Solubility:
Soluble in DMSO.
Physical Properties:
White or off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

size :PriceQuantity 
100 µg$100.00
500 µg$375.00

KT5720 (108068-98-0) is a potent selective protein kinase A inhibitor: PKA (Ki = 60 nM). Displays no effect on PKC or PKG (Ki > 20 μM).1 KT-5720 inhibits axon branching in cultured embryonic rat hippocampal pyramidal neurons.2 Cell permeable.

References/Citations:

1) Kase et al. (1987), K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases; Biochem. Biophys. Res. Commun., 142 436
2) Cabell et al. (1993), Effects of selective inhibition of protein kinase C, cyclic AMP-dependent protein kinase, and Ca(2+)-calmodulin-dependent protein kinase on neurite development in cultured rat hippocampal neurons; Int. J. Dev. Neurosci., 11 357

CAS:
108068-98-0
Catalog Number:
10-2082
Activity:
PKA inhibitor
Molecular Weight:
537.62
Molecular Formula:
C32H31N3O5
Solubility:
Soluble in DMSO.
Physical Properties:
White or off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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