Lactacystin | Proteasome inhibitor
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 200 µg | $126.00 | ||
| 1 mg | $510.00 |
Lactacystin (133343-34-7) is a specific inhibitor of three proteolytic activities of the proteasome. Chymotrypsin-like activity is inhibited most potently followed by trypsin-like activity. Inhibition of the peptidyl-glutamyl peptide hydrolytic activity by lactacystin is relatively weak.
References/Citations:
1) Omura et al. (1991), Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells; J. Antibiot., 44 113
2) Fenteany et al. (1995), Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin; Science, 268 726
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Lactacystin (133343-34-7) is a specific inhibitor of three proteolytic activities of the proteasome. Chymotrypsin-like activity is inhibited most potently followed by trypsin-like activity. Inhibition of the peptidyl-glutamyl peptide hydrolytic activity by lactacystin is relatively weak.
References/Citations:
1) Omura et al. (1991), Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells; J. Antibiot., 44 113
2) Fenteany et al. (1995), Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin; Science, 268 726
Related products
-
Polygodial | TRPA1 activator
From $60.00CAS:6754-20-7Catalog Number:10-1145Activity:TRPA1 activatorChemical Name:(1R,4aS,8aS)-5,5,8a-Trimethyl-1,4,4a,6,7,8-hexahydronaphthalene-1,2-dicarboxaldehydeMolecular Weight:234.34Molecular Formula:C15H22O2Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:Tan waxy solidPurity:97% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
FK-506 | FKBP inhibitor
From $50.00CAS:104987-11-3Catalog Number:10-1103Activity:FKBP inhibitorAlternate Names:TacrolimusMolecular Weight:804.04Molecular Formula:C44H69NO12Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 50 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
Castanospermine | Glucosidase inhibitor
From $50.00CAS:79831-76-8Catalog Number:10-1132Activity:Glycosidase inhibitorChemical Name:(1S,6S,7R,8R,8aR)-1,6,7,8-TetrahydroxyindolizidineMolecular Weight:189.21Molecular Formula:C8H15NO4Solubility:Soluble in Water (up to 25 mg/ml).Physical Properties:White or off-white solidPurity:99% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
