Lactacystin | Proteasome inhibitor
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 200 µg | $126.00 | ||
| 1 mg | $510.00 |
Lactacystin (133343-34-7) is a specific inhibitor of three proteolytic activities of the proteasome. Chymotrypsin-like activity is inhibited most potently followed by trypsin-like activity. Inhibition of the peptidyl-glutamyl peptide hydrolytic activity by lactacystin is relatively weak.
References/Citations:
1) Omura et al. (1991), Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells; J. Antibiot., 44 113
2) Fenteany et al. (1995), Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin; Science, 268 726
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Lactacystin (133343-34-7) is a specific inhibitor of three proteolytic activities of the proteasome. Chymotrypsin-like activity is inhibited most potently followed by trypsin-like activity. Inhibition of the peptidyl-glutamyl peptide hydrolytic activity by lactacystin is relatively weak.
References/Citations:
1) Omura et al. (1991), Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells; J. Antibiot., 44 113
2) Fenteany et al. (1995), Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin; Science, 268 726
Related products
-
Galanthamine HBr | Acetylcholinesterase inhibitor
From $40.00CAS:17991Catalog Number:10-1136Activity:Acetylcholinesterase inhibitorChemical Name:4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol, hydrobromideMolecular Weight:368.27Molecular Formula:C17H21NO3 HBrSolubility:Soluble in DMSO (up to 10 mg/ml) or in Water (up to 12 mg/ml).Physical Properties:Lyophillized solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.Shipping Code:RT -
Ouabain | Na+/K+ ATPase inhibitor
From $30.00CAS:11018-89-6Catalog Number:10-1248Activity:Na+/K+ ATPase inhibitorChemical Name:3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11_,14,19-pentahydoxycard-20(22)-enolide octahydrateMolecular Weight:728.79Molecular Formula:C29H44O12·8(H2O)Solubility:Soluble in DMSO (up to 50 mg/ml), or in Water (up to 10 mg/ml).Physical Properties:White solidPurity:99% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Protect from exposure to moisture. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Castanospermine | Glucosidase inhibitor
From $50.00CAS:79831-76-8Catalog Number:10-1132Activity:Glycosidase inhibitorChemical Name:(1S,6S,7R,8R,8aR)-1,6,7,8-TetrahydroxyindolizidineMolecular Weight:189.21Molecular Formula:C8H15NO4Solubility:Soluble in Water (up to 25 mg/ml).Physical Properties:White or off-white solidPurity:99% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
