LDC1267 | Inhibitor of TAM kinases
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $70.00 | ||
| 25 mg | $270.00 |
LDC1267 (1361030-48-9) is a potent and selective inhibitor of the TAM kinases Tyro3, Axl, and Mer (IC50s respectively: 8 nM, <5 nM, 29 nM).1 It was able to activate the innate immune system and enhance NK killer cell activity to kill cancer metastases in vivo.
References/Citations:
- Paolino et al. (2014), The E3 Ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells; Nature 507 508
C30H26F2N4O5
>98% by HPLC
NMR: (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
LDC1267 (1361030-48-9) is a potent and selective inhibitor of the TAM kinases Tyro3, Axl, and Mer (IC50s respectively: 8 nM, <5 nM, 29 nM).1 It was able to activate the innate immune system and enhance NK killer cell activity to kill cancer metastases in vivo.
References/Citations:
- Paolino et al. (2014), The E3 Ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells; Nature 507 508
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