Lisofylline (racemic) | Anti-diabetic and Antiinflammatory agent
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 10 mg | $50.00 | ||
| 50 mg | $175.00 |
Lisofylline (6493-06-7, racemic) displays anti-inflammatory activity. Regulates immune cell function and autoimmune response by inhibition of IL-12 signalling and cytokine production.1 Protects pancreatic beta cells and prevents type I diabetes in non-obese diabetic mice.2 Lisofylline reduces LPS-induced TNF alpha levels in CD-1 mice.3 Cell permeable.
References/Citations:
1) Yang et al. (2005), Lisofylline: a potential lead for the treatment of diabetes; Biochem. Pharmacol., 69 1
2) Yang et al. (2002), The anti-inflammatory compound lisofylline prevents Type I diabetes in non-obese diabetic mice; Diabetologia, 45 1307
3) Wyska et al. (2010), Pharmacokinetic-pharmacodynamic modeling of methylxanthine derivatives in mice challenged with high-dose lipopolysaccharide; Pharmacology, 85 264
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
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Lisofylline (6493-06-7, racemic) displays anti-inflammatory activity. Regulates immune cell function and autoimmune response by inhibition of IL-12 signalling and cytokine production.1 Protects pancreatic beta cells and prevents type I diabetes in non-obese diabetic mice.2 Lisofylline reduces LPS-induced TNF alpha levels in CD-1 mice.3 Cell permeable.
References/Citations:
1) Yang et al. (2005), Lisofylline: a potential lead for the treatment of diabetes; Biochem. Pharmacol., 69 1
2) Yang et al. (2002), The anti-inflammatory compound lisofylline prevents Type I diabetes in non-obese diabetic mice; Diabetologia, 45 1307
3) Wyska et al. (2010), Pharmacokinetic-pharmacodynamic modeling of methylxanthine derivatives in mice challenged with high-dose lipopolysaccharide; Pharmacology, 85 264
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