M-1 | Enhances mitochondrial fusion

CAS:
219315-22-7
Catalog Number:
10-1598
Activity:
Enhances mitochondrial fusion
Chemical name:
(E)-4-Chloro-2-(1-(2-(2,4,6-trichlorophenyl)hydrazono)ethyl)phenol;
1-(5-Chloro-2-hydroxyphenyl)-ethanone 2-(2,4,6-trichlorophenyl)hydrazone
Molecular Weight:
364.05
Molecular Formula:
C14H10Cl4N2O
Solubility:
Soluble in DMSO (40 mg/ml); ethanol (6 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
5 mg$48.00
25 mg$116.00

M-1 (219315-22-7) enhances mitochondrial fusion without interfering with endoplasmic reticulum (ER) and lysosome morphology.1 M-1 protects cells from mitochondrial fragmentation-associated cell death.2 Promotion of mitochondrial fusion has protective effects in rotenone-induced neurotoxicity.3 Cell permeable.

References/Citations:

  1. Andreaux et al. (2013), Pharmacological approaches to restore mitochondrial function; Nature Rev. Drug Disc., 12 465
  2. Yang et al. (2015), Mitochondrial fusion provides an ‘initial metabolic complementation’ controlled by mtDNA; Cell Mol. Life Sci., 72 2585
  3. Peng et al. (2017), The interaction of mitochondrial Biogenesis and Fission/Fusion Mediated b PGC-1a Regulates Rotenone-Induced Dopaminergic Neurotoxicity; Neurobiol., 54 3783
CAS:
219315-22-7
Catalog Number:
10-1598
Activity:
Enhances mitochondrial fusion
Chemical name:
(E)-4-Chloro-2-(1-(2-(2,4,6-trichlorophenyl)hydrazono)ethyl)phenol;
1-(5-Chloro-2-hydroxyphenyl)-ethanone 2-(2,4,6-trichlorophenyl)hydrazone
Molecular Weight:
364.05
Molecular Formula:
C14H10Cl4N2O
Solubility:
Soluble in DMSO (40 mg/ml); ethanol (6 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

N/A

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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