m-3M3FBS | Phospholipase C activator

CAS:
200933-14-8
Catalog Number:
10-2718
Activity:
Phospholipase C activator
Chemical Name:
2,4,6-Trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide
Molecular Weight:
343.37
Molecular Formula:
C16H16F3NO2S
Solubility:
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 40 mg/ml).
Physical Properties:
Beige solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
10 mg$75.00
50 mg$300.00

m-3M3FBS (200933-14-8) is an activator of phospholipase C (PLC). Stimulates superoxide generation, Ca2+ release and inositol phosphate release in a variety of cell types.1 Inhibits growth of U937 and THP-1 cells.2 m-3M3FBS also affects calcium homeostasis independently of PLC activation.3

References/Citations:

1) Bae et al. (2003), Identification of a compound that directly stimulates phospholipase C activity; Mol. Pharmacol., 63 1043
2) Lee et al. (2005), The novel phospholipase C activator, m-3M3FBS, induces monocytic leukemia cell apoptosis; Cancer Lett., 222 227
3) Krjukova et al. (2004), Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation; Br. J. Pharmacol., 143 3

CAS:
200933-14-8
Catalog Number:
10-2718
Activity:
Phospholipase C activator
Chemical Name:
2,4,6-Trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide
Molecular Weight:
343.37
Molecular Formula:
C16H16F3NO2S
Solubility:
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 40 mg/ml).
Physical Properties:
Beige solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

20% OFF

For Postdoc
Customers!