MCI-186 | Antioxidant
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 50 mg | $35.00 | ||
| 250 mg | $90.00 |
MCI-186 (89-25-8), also known as edaravone, is an antioxidant free radical scavenger used as a neuroprotective agent following acute brain ischemia and subsequent cerebral infarction.1,2 MCI-186 also protects against MPTP-induced neurotoxicity in the Substantia Nigra.3
References/Citations:
1) Watanabe et al. (1994), Protective effects of MCI-186 on cerebral ischemia:possible involvement of free radical scavenging and antioxidant actions; J. Pharmacol. Exp. Ther., 268 1597
2) Yoshida et al. (2006) Neuroprotective effects of edaravone:a novel free radical scavenger in cerebrovascular injury; CNS Drug Reviews, 12 9
3) Kawasaki et al. (2007) Edaravone (3-Methyl-1-phenyl-2-pyrazolin-5-one), a Radical Scavenger, Prevents 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Neurotoxicity in the Substantia Nigra but Not the Striatum; J. Pharmacol. Exp. Ther., 322 274
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
MCI-186 (89-25-8), also known as edaravone, is an antioxidant free radical scavenger used as a neuroprotective agent following acute brain ischemia and subsequent cerebral infarction.1,2 MCI-186 also protects against MPTP-induced neurotoxicity in the Substantia Nigra.3
References/Citations:
1) Watanabe et al. (1994), Protective effects of MCI-186 on cerebral ischemia:possible involvement of free radical scavenging and antioxidant actions; J. Pharmacol. Exp. Ther., 268 1597
2) Yoshida et al. (2006) Neuroprotective effects of edaravone:a novel free radical scavenger in cerebrovascular injury; CNS Drug Reviews, 12 9
3) Kawasaki et al. (2007) Edaravone (3-Methyl-1-phenyl-2-pyrazolin-5-one), a Radical Scavenger, Prevents 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Neurotoxicity in the Substantia Nigra but Not the Striatum; J. Pharmacol. Exp. Ther., 322 274
Related products
-
Dexamethasone | Apoptosis inducing glucocorticoid
From $60.00CAS:50-02-2Catalog Number:10-1134Activity:Apoptosis inducing glucocorticoidChemical Name:(11α,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dioneMolecular Weight:392.46Molecular Formula:C22H29FO5Solubility:Soluble in DMSO (up to 40 mg/ml).Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 monthsShipping Code:RT -
Sivelestat sodium | Leukocyte elastase inhibitor
From $54.00CAS:201677-61-4Catalog Number:10-1102Activity:Leukocyte elastase inhibitorAlternate Names:ONO-5046Chemical Name:N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine sodium hydrateMolecular Weight:528.51Molecular Formula:C20H21N2O7S·Na·4H2OSolubility:Soluble in DMSO (up to 20 mg/ml).Physical Properties:White solidPurity:98% by HPLCStorage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 monthsShipping Code:RT -
Rolipram | PDE4 inhibitor
From $48.00CAS:61413-54-5Catalog Number:10-1079Activity:PDE4 inhibitorAlternate Names:ZK 62711Chemical Name:4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone (racemic)Molecular Weight:275.35Molecular Formula:C16H21NO3Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:White or off-white solidPurity:98% by TLC
NMR conformsStorage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
