Mdivi | Mitochondrial division inhibitor

CAS:
338967-87-6
Catalog Number:
10-1179
Activity:
Mitochondrial division inhibitor
Chemical Name:
3-(2,4-Dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone
Molecular Weight:
353.23
Molecular Formula:
C15H10Cl2N2O2S
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

size :PriceQuantity 
5 mg$48.00
25 mg$186.00

Mdivi (338967-87-6) is a selective inhibitor of Dnm1 GTPase (IC50=1-10 μM). Inhibits mitochondrial outer membrane permeabilization. Mdivi inhibits mitochondrial division and apoptosis. Cell permeable.

References/Citations:

1) Cassidy-Stone et al. (2008), Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization; Dev. Cell, 14 193
2) Lackner et al. (2010), Small molecule inhibitors of mitochondrial division: tools that translate basic biological research into medicine; Chem. Biol., 17 578

CAS:
338967-87-6
Catalog Number:
10-1179
Activity:
Mitochondrial division inhibitor
Chemical Name:
3-(2,4-Dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone
Molecular Weight:
353.23
Molecular Formula:
C15H10Cl2N2O2S
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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