Mdivi | Mitochondrial division inhibitor
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $48.00 | ||
| 25 mg | $186.00 |
Mdivi (338967-87-6) is a selective inhibitor of Dnm1 GTPase (IC50=1-10 μM). Inhibits mitochondrial outer membrane permeabilization. Mdivi inhibits mitochondrial division and apoptosis. Cell permeable.
References/Citations:
1) Cassidy-Stone et al. (2008), Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization; Dev. Cell, 14 193
2) Lackner et al. (2010), Small molecule inhibitors of mitochondrial division: tools that translate basic biological research into medicine; Chem. Biol., 17 578
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Mdivi (338967-87-6) is a selective inhibitor of Dnm1 GTPase (IC50=1-10 μM). Inhibits mitochondrial outer membrane permeabilization. Mdivi inhibits mitochondrial division and apoptosis. Cell permeable.
References/Citations:
1) Cassidy-Stone et al. (2008), Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization; Dev. Cell, 14 193
2) Lackner et al. (2010), Small molecule inhibitors of mitochondrial division: tools that translate basic biological research into medicine; Chem. Biol., 17 578
Related products
-
MitoBloCK-6 | Mitochondrial import inhibitor
From $60.00CAS:303215-67-0Catalog Number:10-1472Activity:Mitochondrial import inhibitorChemical Name:2-[[(4-Anilinophenyl)imino]methyl]-4,6-dichlorophenolMolecular Weight:357.24Molecular Formula:C19H14Cl2N2OSolubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 6 mg/ml with warming).Physical Properties:Orange solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT -
PK-11195 | Mitochondrial benzodiazepine receptor ligand
From $35.00CAS:85532-75-8Catalog Number:10-2221Activity:Mitochondrial benzodiazepine receptor ligandChemical Name:1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamideMolecular Weight:352.86Molecular Formula:C21H21ClN2OSolubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml).Physical Properties:White solidStorage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored under nitrogen or argon at -20° for up to 1 month.Shipping Code:RT -
Nigericin Na | Induces rapid intracellular acidification
From $50.00CAS:28643-80-3Catalog Number:10-2089Activity:Induces rapid intracellular acidificationAlternate Names:Antibiotic K178, Antibiotic X-464, Azalomycin M, PolyetherinAMolecular Weight:746.96Molecular Formula:C40H57O11 NaSolubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 20 mg/ml).Physical Properties:White solidPurity:98% by TLCStorage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
