ME-0328 | PARP3 inhibitor

CAS:
1445251-22-8
Catalog Number:
10-1484
Activity:
PARP3 inhibitor
Chemical Name:
3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide
Molecular Weight:
321.38
Molecular Formula:
C19H19N3O2
Solubility:
Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 4 mg/ml with warming).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

size :PriceQuantity 
5 mg$70.00
25 mg$200.00

ME-0328 (1445251-22-8) is a potent and selective PARP3 inhibitor (IC50=0.89 μM). Selective over PARP-1, PARP-2 and other ARDT enzymes (IC50=6.3, 10.8 and >30 μM respectively).

References/Citations:

1) Lindgren et al. (2013), PARP Inhibitor with Selectivity Toward ADP-Ribosyltransferase ART3/PARP3; ACS Chem. Biol.,8 1689

CAS:
1445251-22-8
Catalog Number:
10-1484
Activity:
PARP3 inhibitor
Chemical Name:
3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide
Molecular Weight:
321.38
Molecular Formula:
C19H19N3O2
Solubility:
Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 4 mg/ml with warming).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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