Mifepristone | Glucocorticoid antagonist
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 100 mg | $50.00 | ||
| 500 mg | $100.00 |
Mifepristone (84371-65-3) is a cell-permeable steroid that is a potent antagonist at the progesterone and glucocorticoid receptors.1 It is used clinically as an abortifacient. KD progesterone receptor = 2.6 nM2 and KD glucocorticoid receptor = 0.4 nM3.
References/Citations:
1) Cadepond et al. (1997) RU486 (Mifepristone): Mechanisms of action and clinical uses; Annu. Rev. Med. 48 129
2) Terakawa et al. (1988) RU486, a progestin antagonist, binds to progesterone receptors in a human endometrial cancer cell line and reverses the growth inhibition by progestins; J. Steroid Biochem. 31 161
3) Jung-Testas and Baulieu (1983) Inhibition of glucocorticosteroid action in cultured L-929 mouse fibroblasts by RU486, a new anti-glucocorticosteroid of high affinity for the glucocorticoidsteroid receptor; Exp. Cell Res. 147 177
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Mifepristone (84371-65-3) is a cell-permeable steroid that is a potent antagonist at the progesterone and glucocorticoid receptors.1 It is used clinically as an abortifacient. KD progesterone receptor = 2.6 nM2 and KD glucocorticoid receptor = 0.4 nM3.
References/Citations:
1) Cadepond et al. (1997) RU486 (Mifepristone): Mechanisms of action and clinical uses; Annu. Rev. Med. 48 129
2) Terakawa et al. (1988) RU486, a progestin antagonist, binds to progesterone receptors in a human endometrial cancer cell line and reverses the growth inhibition by progestins; J. Steroid Biochem. 31 161
3) Jung-Testas and Baulieu (1983) Inhibition of glucocorticosteroid action in cultured L-929 mouse fibroblasts by RU486, a new anti-glucocorticosteroid of high affinity for the glucocorticoidsteroid receptor; Exp. Cell Res. 147 177
Related products
-
Simvastatin | HMG-CoA reductase inhibitor
From $50.00CAS:79902-63-9Catalog Number:10-1018Activity:HMG-CoA reductase inhibitorAlternate Names:MevinolinChemical Name:2,2-Dimethyl-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester butanoic acidMolecular Weight:418.58Molecular Formula:C25H38O5Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 35 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
Nalmefene HCl | Opioid receptor antagonist
From $100.00CAS:58895-64-0Catalog Number:10-1049Activity:Opioid receptor antagonistChemical Name:5(α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylene-morphinan-3,14-diol hydrochlorideMolecular Weight:375.82Molecular Formula:C21H25NO3·HClSolubility:Soluble in Water (up to 25 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.Shipping Code:RT -
Mupirocin | Antibiotic
From $80.00CAS:12650-69-0Catalog Number:10-1101Activity:AntibioticAlternate Names:Pseudomonic acid AMolecular Weight:500.63Molecular Formula:C26H44O9Solubility:Soluble in DMSO (up to 20 mg/ml).Physical Properties:Hygroscopic colorless wax/amorphous solidPurity:>98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
