Miglitol | beta-glucosidase inhibitor / antidiabetic

CAS:
72432-03-2
Catalog Number:
10-2332
Activity:
α-glucosidase inhibitor / antidiabetic
Alternate Names:
N-(2-Hydroxyethyl)-1-deoxynojirimycin; BAY-1099
Chemical Name:
(2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
Molecular Weight:
207.23
Molecular Formula:
C8H17NO5
Solubility:
Soluble in DMSO (up to 50 mg/ml with warming), or in Water (up to 60 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
20 mg$70.00
100 mg$230.00

Miglitol (72432-03-2) is an α-glucosidase inhibitor which induces an enhanced and prolonged release of glucagon-like peptide-1, regulating appetite and stabilizing body weight in humans.1 Miglitol displays anti-atherothrombotic effect by reducing platelet activation2 and raising circulating adiponectin levels3 in patients with type 2 diabetes. Clinically useful antidiabetic agent.

References/Citations:

1) Lee et al. (2002), The effects of miglitol on glucagon-like peptide-1 secretion and appetite sensations in obese type 2 diabetics; Diabetes Obes. Metab., 4 329
2) Nomura et al. (2011), Effects of miglitol in platelet-derived microparticle, adiponectin, and selectin level in patients with type 2 diabetes mellitus; Int. J. Gen. Med., 4 539
3) Yokoyama et al. (2007), Miglitol increases the adiponectin level and decreases urinary albumin excretion in patients with type 2 diabetes mellitus; Metabolism, 56 1458

CAS:
72432-03-2
Catalog Number:
10-2332
Activity:
α-glucosidase inhibitor / antidiabetic
Alternate Names:
N-(2-Hydroxyethyl)-1-deoxynojirimycin; BAY-1099
Chemical Name:
(2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
Molecular Weight:
207.23
Molecular Formula:
C8H17NO5
Solubility:
Soluble in DMSO (up to 50 mg/ml with warming), or in Water (up to 60 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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