Minoxidil | KATP channel opener

CAS:
38304-91-5
Catalog Number:
10-1214
Activity:
KATP channel opener
Chemical Name:
6-Piperidine-1-ylpyrimidine-2,4-diamine 3-oxide
Molecular Weight:
209.25
Molecular Formula:
C9H15N5O
Solubility:
Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

size :PriceQuantity 
100 mg$50.00
500 mg$200.00

Minoxidil (38304-91-5) is a direct antihypertensive peripheral vasodilator acting via activation of KATP channels leading to relaxation of smooth muscle.1 Active metabolite is minoxidil sulfate (IC50 = 0.14 μM). Minoxidil is mainly used as a treatment for alopecia because of its observed hair regrowth ability.2

References/Citations:

1) Meisheri et al. (1988), Mechanism of action of minoxidil sulfate-induced vasodilation: a role for increased K+ permeability; J. Pharmacol. Exp. Ther., 245 7
2) Messenger and Rundegren (2004) Minoxidil:mechanisms of action on hair growth; Br. J. Dermatol., 150 186

CAS:
38304-91-5
Catalog Number:
10-1214
Activity:
KATP channel opener
Chemical Name:
6-Piperidine-1-ylpyrimidine-2,4-diamine 3-oxide
Molecular Weight:
209.25
Molecular Formula:
C9H15N5O
Solubility:
Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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