MitoBloCK-10 | TIMM44 blocker
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $60.00 | ||
| 25 mg | $240.00 |
MitoBloCK-10 (394694-98-5) is a first in class TIMM44 blocker. Translocase of inner mitochondrial membrane 44 (TIMM44) is essential for maintaining function and integrity of mitochondria.1 It induced mitochondrial dysfunction and suppressed angiogenic activity in endothelial cells.1 Targeting TIMM44 by MitoBloCK-10 significantly inhibits bladder cancer cell growth in vitro and in vivo.2
References/Citations:
- Ma et al. (2023), The mitochondrial protein TIMM44 is required for angiogenesis in vitro and in vivo; Cell Death Dis. 14 307
- Zhang et al. (2024), A first-in-class TIMM44 blocker inhibits bladder cancer cell growth; Cell Death Dis. 15 204
C12H8FN3O3S
>98% TLC
NMR: (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
MitoBloCK-10 (394694-98-5) is a first in class TIMM44 blocker. Translocase of inner mitochondrial membrane 44 (TIMM44) is essential for maintaining function and integrity of mitochondria.1 It induced mitochondrial dysfunction and suppressed angiogenic activity in endothelial cells.1 Targeting TIMM44 by MitoBloCK-10 significantly inhibits bladder cancer cell growth in vitro and in vivo.2
References/Citations:
- Ma et al. (2023), The mitochondrial protein TIMM44 is required for angiogenesis in vitro and in vivo; Cell Death Dis. 14 307
- Zhang et al. (2024), A first-in-class TIMM44 blocker inhibits bladder cancer cell growth; Cell Death Dis. 15 204
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