Mitoquinone mesylate | Mitochondria-targeted antioxidant
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $70.00 | ||
| 25 mg | $240.00 |
Mitoquinone mesylate (845959-50-4) is a mitochondria-targeted antioxidant. Displays cardio- and neuroprotective effects.1 Displays beneficial effects in mouse models of Alzheimer’s disease.2,3 Protects pancreatic β-cells against oxidative stress and improves insulin secretion.4 Inhibits respiratory syncytial virus (RSV) production via lowering of mitochondrial ROS levels.5 Cell permeable.
References/Citations:
- Ghosh et al. (2010), Neuroprotection by a mitochondria-targeted drug in a Parkinson’s disease model; Free Radic. Biol. Med., 49 1674
- McManus et al. (2011), The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer’s disease; J. Neurosci., 31 15703
- Young and Franklin, (2019), The mitochondria-targeted antioxidant MitoQ inhibits memory loss, neuropathology, and extends lifespan in aged 3xTg-AD mice; Cell Neurosci. 101 103409
- Lim et al. (2011), Mitochondria-targeted antioxidants protect pancreatic b-cells against oxidative stress and improve insulin secretion in glucotoxicity and glucolipotoxicity; Cell Physiol. Biochem., 28 873
- MengJie et al. (2019), Subversion of Host Cell Mitochondria by RSV to Favor Virus Production in Dependent on Inhibition of Mitochondrial Complex I and ROS Generation; Cells 8 1417
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Mitoquinone mesylate (845959-50-4) is a mitochondria-targeted antioxidant. Displays cardio- and neuroprotective effects.1 Displays beneficial effects in mouse models of Alzheimer’s disease.2,3 Protects pancreatic β-cells against oxidative stress and improves insulin secretion.4 Inhibits respiratory syncytial virus (RSV) production via lowering of mitochondrial ROS levels.5 Cell permeable.
References/Citations:
- Ghosh et al. (2010), Neuroprotection by a mitochondria-targeted drug in a Parkinson’s disease model; Free Radic. Biol. Med., 49 1674
- McManus et al. (2011), The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer’s disease; J. Neurosci., 31 15703
- Young and Franklin, (2019), The mitochondria-targeted antioxidant MitoQ inhibits memory loss, neuropathology, and extends lifespan in aged 3xTg-AD mice; Cell Neurosci. 101 103409
- Lim et al. (2011), Mitochondria-targeted antioxidants protect pancreatic b-cells against oxidative stress and improve insulin secretion in glucotoxicity and glucolipotoxicity; Cell Physiol. Biochem., 28 873
- MengJie et al. (2019), Subversion of Host Cell Mitochondria by RSV to Favor Virus Production in Dependent on Inhibition of Mitochondrial Complex I and ROS Generation; Cells 8 1417
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