ML167 | Clk4 inhibitor

CAS:
1285702-20-6
Catalog Number:
10-4543
Activity:
Clk4 inhibitor
Chemical Name:
[5-[4-[(5-Methylfuran-2-yl)methylamino]quinazolin-6-yl]furan-2-yl]methanol
Molecular Weight:
335.36
Molecular Formula:
C19H17N2O3
Solubility:
Soluble in DMSO (greater than 25 mg/ml).
Physical Properties:
White solid
Purity:
>98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
5 mg$75.00
25 mg$295.00
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ML167 (1285702-20-6) is a highly selective cell permeable inhibitor of Cdc2-like kinase 4 (Clk4) – IC50 = 136nM. It displays at least 10-fold greater selectivity over the related kinases Clk1(1.52 μM), Clk2(1.65μM), Clk3(>10μM), Dyrk1A(>10μM), and Dyrk1B(4.4 μM).

References/Citations:

1) Rosenthal et al. (2010), An inhibitor of the Cdc2-like kinase 4 (Clk4); Probe Reports from the NIH Molecular Libraries Program

CAS:
1285702-20-6
Catalog Number:
10-4543
Activity:
Clk4 inhibitor
Chemical Name:
[5-[4-[(5-Methylfuran-2-yl)methylamino]quinazolin-6-yl]furan-2-yl]methanol
Molecular Weight:
335.36
Molecular Formula:
C19H17N2O3
Solubility:
Soluble in DMSO (greater than 25 mg/ml).
Physical Properties:
White solid
Purity:
>98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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