ML300 | SARS-CoV 3CL protease inhibitor
CAS:
N/A
Catalog Number:
10-4961
Activity:
SARS-CoV 3CL protease inhibitor
Chemical Names:
N-(4-(2-(1H-Benzo[d][1,2,3]triazol-1-yl)-N-(thiophen-3-ylmethyl)acetamido)phenyl)cyclopropanecarboxamide
Molecular Weight:
431.51
Molecular Formula:
C23H21N5O2S
Solubility:
Soluble in DMSO (>25 mg/ml)
Physical Properties:
Off-white solid
Purity:
>98% TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Shipping Code:
RT
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 10 mg | $75.00 | ||
| 50 mg | $250.00 |
ML300 is a selective non-covalent inhibitor of SARS-CoV 3CL protease (IC50 = 4.11 µM).1,2
References:
- Turlington et al. (2012) Non-covalent triazole-based inhibitors of the SARS main protease 3CLpro; In: Probe Reports from the NIH Molecular Libraries Program
- Turlington et al. (2013) Discovery of N-(Benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl)carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding; Bioorg. Med. Chem. Lett. 23 6172
CAS:
N/A
Catalog Number:
10-4961
Activity:
SARS-CoV 3CL protease inhibitor
Chemical Names:
N-(4-(2-(1H-Benzo[d][1,2,3]triazol-1-yl)-N-(thiophen-3-ylmethyl)acetamido)phenyl)cyclopropanecarboxamide
Molecular Weight:
431.51
Molecular Formula:
C23H21N5O2S
Solubility:
Soluble in DMSO (>25 mg/ml)
Physical Properties:
Off-white solid
Purity:
>98% TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Shipping Code:
RT
Safety Data Sheet:
N/A
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
ML300 is a selective non-covalent inhibitor of SARS-CoV 3CL protease (IC50 = 4.11 µM).1,2
References:
- Turlington et al. (2012) Non-covalent triazole-based inhibitors of the SARS main protease 3CLpro; In: Probe Reports from the NIH Molecular Libraries Program
- Turlington et al. (2013) Discovery of N-(Benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl)carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding; Bioorg. Med. Chem. Lett. 23 6172
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