ML418 | Kir7.1/6.2 blocker
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $70.00 | ||
| 25 mg | $225.00 |
ML418 (1928763-08-9) is a blocker of the inward rectifier potassium channels Kir7.1 (IC50 = 310nM) and Kir6.2 (equipotent) with metabolic and pharmacokinetic parameters suitable for in vivo research.1 Greater than 23-fold selectivity over Kir1.1, Kir2.1, Kir2.2, Kir2.3, Kir4.1.
References/Citations:
- Swale et al. (2016), ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels; ACS Chem. Neurosci. 7 1013
C19H24ClN3O3
>98% by HPLC
NMR: (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
ML418 (1928763-08-9) is a blocker of the inward rectifier potassium channels Kir7.1 (IC50 = 310nM) and Kir6.2 (equipotent) with metabolic and pharmacokinetic parameters suitable for in vivo research.1 Greater than 23-fold selectivity over Kir1.1, Kir2.1, Kir2.2, Kir2.3, Kir4.1.
References/Citations:
- Swale et al. (2016), ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels; ACS Chem. Neurosci. 7 1013
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