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MLS-532223 | GTPase inhibitor
CAS:
16616-39-0
Catalog Number:
10-1305
Activity:
GTPase inhibitor
Chemical Name:
1-(3-Nitrophenyl)-3-phenyl-2-propyn-1-one
Molecular Weight:
251.24
Molecular Formula:
C15H9NO3
Solubility:
Soluble in DMSO (up to 20 mg/ml).
Physical Properties:
Beige solid
Purity:
98% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
RT (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Shipping Code:
RT
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $62.00 | ||
| 25 mg | $248.00 |
MLS-532223 (16616-39-0) is a high-affinity selective inhibitor of Rho family GTPases (EC50=10 μM). It inhibits EGF-stimulated Rac1 activation (3-10 μM). Cell permeable.
References/Citations:
1) Surviladze et al. (2010), Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay; J. Biomol. Screening, 15 10
16616-39-0, GTPase inhibitor, MLS-532223, MLS-532223 supplier, MLS532223
CAS:
16616-39-0
Catalog Number:
10-1305
Activity:
GTPase inhibitor
Chemical Name:
1-(3-Nitrophenyl)-3-phenyl-2-propyn-1-one
Molecular Weight:
251.24
Molecular Formula:
C15H9NO3
Solubility:
Soluble in DMSO (up to 20 mg/ml).
Physical Properties:
Beige solid
Purity:
98% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
RT (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Shipping Code:
RT
Safety Data Sheet:
N/A
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
MLS-532223 (16616-39-0) is a high-affinity selective inhibitor of Rho family GTPases (EC50=10 μM). It inhibits EGF-stimulated Rac1 activation (3-10 μM). Cell permeable.
References/Citations:
1) Surviladze et al. (2010), Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay; J. Biomol. Screening, 15 10
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