MRL-24 | PPAR gamma partial agonist
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $65.00 | ||
| 25 mg | $260.00 |
MRL-24 (393794-17-7) displays high affinity for PPARγ with excellent anti-diabetic activity in mice but poor PPARγ agonist activity in transcription and adipogenesis assays. MRL-24 is highly effective (30 nM) at blocking Cdk5-mediated phosphorylation of PPARγ. Cell permeable.
References/Citations:
1) Choi et al. (2010), Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by CDK5; Nature, 466 451
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
MRL-24 (393794-17-7) displays high affinity for PPARγ with excellent anti-diabetic activity in mice but poor PPARγ agonist activity in transcription and adipogenesis assays. MRL-24 is highly effective (30 nM) at blocking Cdk5-mediated phosphorylation of PPARγ. Cell permeable.
References/Citations:
1) Choi et al. (2010), Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by CDK5; Nature, 466 451
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