N-Myristoylglycine | Endogenous brown fat-inducing lipid
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $65.00 | ||
| 25 mg | $260.00 |
N-Myristoylglycine (14246-55-0) is an endogenous lipid which was found to differentiate adipocyte precursors and white-biased adipocytes into functional brown adipocytes.1 Blood plasma and urine biomarker of primary dysmenorrhea.2 A standard for analysis of N-terminal myristoylated peptides and proteins.3,4 Enzymatically produced in mammals from myristoyl-coenzyme A and glycine by acyl-CoA:glycine N-acyltransferase.5
References/Citations:
- Guijas et al. (2022), Drug-Initiated Activity Metabolomics Identifies Myristoylglycine as a Potent Endogenous Metabolite for Human Brown Fat Differentiation; Metabolites, 12 749
- Liu et al. (2013), Biomarkers of primary dysmenorrhea and herbal formula intervention: an exploratory metabonomics study of blood plasma and urine; Mol. Biosyst., 9 77
- Okimura et al. (2003), HPLC analysis of fatty acyl-glycine in the aqueous methanesulfonic acid hydrolysates of N-terminally fatty acylated peptides; Biol. Pharm. Bull., 26 1166
- Resh et al. (2016), Fatty acylation of proteins: The long and the short of it; Prog. Lipid Res., 63 120
- Merkler et al. (1996), Fatty acid amide biosynthesis: a possible new role for peptidylglycine alpha-amidating enzyme and acyl-coenzyme A: glycine N-acyltransferase; Arch. Biochem. Biophys., 330 430
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
N-Myristoylglycine (14246-55-0) is an endogenous lipid which was found to differentiate adipocyte precursors and white-biased adipocytes into functional brown adipocytes.1 Blood plasma and urine biomarker of primary dysmenorrhea.2 A standard for analysis of N-terminal myristoylated peptides and proteins.3,4 Enzymatically produced in mammals from myristoyl-coenzyme A and glycine by acyl-CoA:glycine N-acyltransferase.5
References/Citations:
- Guijas et al. (2022), Drug-Initiated Activity Metabolomics Identifies Myristoylglycine as a Potent Endogenous Metabolite for Human Brown Fat Differentiation; Metabolites, 12 749
- Liu et al. (2013), Biomarkers of primary dysmenorrhea and herbal formula intervention: an exploratory metabonomics study of blood plasma and urine; Mol. Biosyst., 9 77
- Okimura et al. (2003), HPLC analysis of fatty acyl-glycine in the aqueous methanesulfonic acid hydrolysates of N-terminally fatty acylated peptides; Biol. Pharm. Bull., 26 1166
- Resh et al. (2016), Fatty acylation of proteins: The long and the short of it; Prog. Lipid Res., 63 120
- Merkler et al. (1996), Fatty acid amide biosynthesis: a possible new role for peptidylglycine alpha-amidating enzyme and acyl-coenzyme A: glycine N-acyltransferase; Arch. Biochem. Biophys., 330 430
Related products
-
Rucaparib phosphate | PARP1 inhibitor
From $70.00CAS:459868-92-9Catalog Number:10-3321Activity:PARP1 inhibitorChemical Name:8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-oneAlternate Name:AG-14699; PF01367338Molecular Weight:421.36Molecular Formula:C19H18FN3O • H3PO4Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Ibrutinib | BTK inhibitor
From $40.00CAS:936563-96-1Catalog Number:10-4757Alternate Name:PCI-32765Activity:BTK inhibitor/Cancer immunotherapy enhancerChemical Name:1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-oneMolecular Weight:440.51Molecular Formula:C25H24N6O2Solubility:Soluble in DMSO ( up to at least 25 mg/ml)Physical Properties:White or off-white solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
