N-Myristoylglycine | Endogenous brown fat-inducing lipid
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $65.00 | ||
| 25 mg | $260.00 |
N-Myristoylglycine (14246-55-0) is an endogenous lipid which was found to differentiate adipocyte precursors and white-biased adipocytes into functional brown adipocytes.1 Blood plasma and urine biomarker of primary dysmenorrhea.2 A standard for analysis of N-terminal myristoylated peptides and proteins.3,4 Enzymatically produced in mammals from myristoyl-coenzyme A and glycine by acyl-CoA:glycine N-acyltransferase.5
References/Citations:
- Guijas et al. (2022), Drug-Initiated Activity Metabolomics Identifies Myristoylglycine as a Potent Endogenous Metabolite for Human Brown Fat Differentiation; Metabolites, 12 749
- Liu et al. (2013), Biomarkers of primary dysmenorrhea and herbal formula intervention: an exploratory metabonomics study of blood plasma and urine; Mol. Biosyst., 9 77
- Okimura et al. (2003), HPLC analysis of fatty acyl-glycine in the aqueous methanesulfonic acid hydrolysates of N-terminally fatty acylated peptides; Biol. Pharm. Bull., 26 1166
- Resh et al. (2016), Fatty acylation of proteins: The long and the short of it; Prog. Lipid Res., 63 120
- Merkler et al. (1996), Fatty acid amide biosynthesis: a possible new role for peptidylglycine alpha-amidating enzyme and acyl-coenzyme A: glycine N-acyltransferase; Arch. Biochem. Biophys., 330 430
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
N-Myristoylglycine (14246-55-0) is an endogenous lipid which was found to differentiate adipocyte precursors and white-biased adipocytes into functional brown adipocytes.1 Blood plasma and urine biomarker of primary dysmenorrhea.2 A standard for analysis of N-terminal myristoylated peptides and proteins.3,4 Enzymatically produced in mammals from myristoyl-coenzyme A and glycine by acyl-CoA:glycine N-acyltransferase.5
References/Citations:
- Guijas et al. (2022), Drug-Initiated Activity Metabolomics Identifies Myristoylglycine as a Potent Endogenous Metabolite for Human Brown Fat Differentiation; Metabolites, 12 749
- Liu et al. (2013), Biomarkers of primary dysmenorrhea and herbal formula intervention: an exploratory metabonomics study of blood plasma and urine; Mol. Biosyst., 9 77
- Okimura et al. (2003), HPLC analysis of fatty acyl-glycine in the aqueous methanesulfonic acid hydrolysates of N-terminally fatty acylated peptides; Biol. Pharm. Bull., 26 1166
- Resh et al. (2016), Fatty acylation of proteins: The long and the short of it; Prog. Lipid Res., 63 120
- Merkler et al. (1996), Fatty acid amide biosynthesis: a possible new role for peptidylglycine alpha-amidating enzyme and acyl-coenzyme A: glycine N-acyltransferase; Arch. Biochem. Biophys., 330 430
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